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Rheumatology
Nontuberculous mycobacterial infection in rheumatoid arthritis patients: a single-center experience in South Korea
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Doo-Ho Lim, Yong-Gil Kim, Tae Sun Shim, Kyung-Wook Jo, Byeongzu Ghang, Soo Min Ahn, Seokchan Hong, Chang-Keun Lee, Bin Yoo
Korean J Intern Med. 2017;32(6):1090-1097. Published online January 6, 2017
Background/Aims: Nontuberculous mycobacteria (NTM) infection has been increasing worldwide in both general population and immunocompromised patients, which has also been reported in rheumatoid arthritis (RA) patients. This study aimed to identify the incidence and clinical characteristics of NTM inf..
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Impact of early diagnosis on functional disability in rheumatoid arthritis
Dam Kim, Chan-Bum Choi, Jiyoung Lee, Soo-Kyung Cho, Soyoung Won, So-Young Bang, Hoon-Suk Cha, Jung-Yoon Choe, Won Tae Chung, Seung-Jae Hong, Jae-Bum Jun, Young Ok Jung, Jinseok Kim, Seong-Kyu Kim, Tae-Hwan Kim, Tae-Jong Kim, Eunmi Koh, Hye-Soon Lee, Jaejoon Lee, Jisoo Lee, Sang-Heon Lee, Shin-Seok Lee, Sung Won Lee, Seung-Cheol Shim, Dae-Hyun Yoo, Bo Young Yoon, Yoon-Kyoung Sung, Sang-Cheol Bae; KORONA investigators
Korean J Intern Med. 2017;32(4):738-746. Published online September 13, 2016
Background/Aims: To determine whether early diagnosis is beneficial for functional status of various disease durations in rheumatoid arthritis (RA) patients.
Methods: A total of 4,540 RA patients were enrolled as part of the Korean Observational Study Network for Arthritis (KORONA). We defined earl..
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Comparative efficacy of biological agents in methotrexate-refractory rheumatoid arthritis patients: a Bayesian mixed treatment comparison
Miyoung Choi, Min Kyung Hyun, Seongmi Choi, Ha Jin Tchoe, Sung Yeon Lee, Kyeong Min Son, Min-Jeong Kim, Young Ok Jung, Hyun Ah Kim
Korean J Intern Med. 2017;32(3):536-547. Published online June 2, 2016
Background/Aims: Biological agents (biologics) targeting proinflammatory signaling have emerged as an important treatment option in rheumatoid arthritis (RA). Despite the clinical effectiveness of biologics for patients with RA who do not respond to ‘traditional’ disease-modifying anti-rheumatic ..
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Periodontitis is associated with rheumatoid arthritis: a study with longstanding rheumatoid arthritis patients in Korea
In Ah Choi, Jin-Hee Kim, Yong Mi Kim, Joo Youn Lee, Kyung Hwa Kim, Eun Young Lee, Eun Bong Lee, Yong-Moo Lee, Yeong Wook Song
Korean J Intern Med. 2016;31(5):977-986. Published online March 25, 2016
Background/Aims: A cross-sectional study was undertaken to investigate the association between severity of periodontitis and clinical manifestation of rheumatoid arthritis (RA).
Methods: Two hundred sixty-four RA patients and 88 age- and sex-matched controls underwent dental exam. Additionally, cli..
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Hemato-oncology
Clinical manifestations of autoimmune disease-related non-Hodgkin lymphoma: a Korean single-center, retrospective clinical study
Young-Woo Jeon, Jae-Ho Yoon, Sung-Eun Lee, Ki-Seong Eom, Yoo-Jin Kim, Hee-Je Kim, Seok Lee, Chang-Ki Min, Jong Wook Lee, Woo-Sung Min, Seok-Goo Cho
Korean J Intern Med. 2015;31(5):944-952. Published online July 7, 2016
Background/Aims: Recently, large cohort studies regarding associations between autoimmune disease and lymphomas have been reported in a few Western countries. However, Asian data concerning autoimmune-related lymphomas are limited. Therefore, we evaluated the clinical characteristics and prognostic ..
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Rheumatology
Efficacy and safety of low-dose tacrolimus for active rheumatoid arthritis with an inadequate
response to methotrexate
Won-Seok Lee, Sang-Il Lee, Myeung-Soo Lee, Sung-Il Kim, Shin-Seok Lee, Wan-Hee Yoo
Korean J Intern Med. 2016;31(4):779-787. Published online March 10, 2016
Background/Aims: To determine the efficacy and safety of low-dose tacrolimus in Korean rheumatoid arthritis (RA) subjects with an inadequate response to methotrexate (MTX).
Methods: This was a multicenter, open-label study conducted at five Korean sites. Fifty-six patients with active RA, despite t..
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Macrophage migration inhibitory factor: a potential therapeutic target for rheumatoid arthritis
Kyoung-Woon Kim, Hae-Rim Kim
Korean J Intern Med. 2016;31(4):634-642. Published online May 12, 2016
Macrophage migration inhibitory factor (MIF) is originally identified in the culture medium of activated T lymphocytes as a soluble factor that inhibits the random migration of macrophages. MIF is now recognized as a multipotent cytokine involved in the regulation of immune and inf lammatory respons..
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Prosthetic knee joint infection due to Listeria monocytogenes bacteremia in a diabetic female
Yun Seo, Yong-sun Noh, Seong-Heon Wie, U-Im Chang
Korean J Intern Med. 2016;31(3):616-619. Published online January 27, 2016
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Cyclophosphamide therapy for secondary amyloidosis in a patient with juvenile idiopathic arthritis unresponsive to tumor necrosis factor α inhibitor therapy
Sun Ae Han, Young Min Yoon, Wan Soo Lee, Yun Sung Kim, Byung Chul Shin, Jong Hoon Chung, Hyun Lee Kim
Korean J Intern Med. 2016;31(3):601-604. Published online March 7, 2016
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Rheumatology
An analysis of age-related loss of skeletal muscle mass and its significance on osteoarthritis in a Korean population
Hun-Tae Kim, Hyun-Je Kim, Hee-Yun Ahn, Young-Hoon Hong
Korean J Intern Med. 2016;31(3):585-593. Published online March 15, 2016
Background/Aims: This study was conducted in order to analyze the effects of sarcopenia on age-related osteoarthritis (OA) of the knee in a Korean population.
Methods: All the Korean subjects who visited the Yeungnam University Medical Center Health Promotion Center between 2008 and 2012 in order t..
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The specialist physician’s approach to rheumatoid arthritis in South Africa
Frederik C. J. Bester, Fredricka J. Bosch, Barend J. Jansen van Rensburg
Korean J Intern Med. 2016;31(2):219-236. Published online February 26, 2016
Rheumatoid arthritis (RA) is expected to increase in Africa and South Africa. Due to the low numbers of rheumatologists in South Africa, specialist physicians also have to care for patients with RA. Furthermore several new developments have taken place in recent years which improved the management a..
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Current concepts in the management of rheumatoid arthritis
Yoshiya Tanaka
Korean J Intern Med. 2016;31(2):210-218. Published online February 26, 2016
Rheumatoid arthritis (RA) is a systemic autoimmune disease characterized by inflammation and joint destruction that causes significant morbidity and mortality. However, the combined use of methotrexate, a synthetic disease-modifying antirheumatic drug (DMARD), and biologic DMARD has revolutionized t..
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Sleep quality in rheumatoid arthritis, and its association with disease activity in a Korean population
Chang-Nam Son, Go Choi, So-Yeon Lee, Ji-Min Lee, Tae-Han Lee, Hye-Jin Jeong, Chang-Gyu Jung, Ji-Min Kim, Yong-Won Cho, Sang-Hyon Kim
Korean J Intern Med. 2015;30(3):384-390. Published online April 29, 2015
Background/Aims: The aim of this study was to compare the sleep quality between rheumatoid arthritis (RA) patients and healthy controls; and to evaluate the relationship between RA disease activity and sleep quality in Korea.
Methods: A total of 130 RA patients and 67 age- and sex-matched healthy c..
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Mortality in patients with rheumatoid arthritis-associated interstitial lung disease treated with an anti-tumor necrosis factor agent
Bon San Koo, Seokchan Hong, You Jae Kim, Yong-Gil Kim, Chang-Keun Lee, Bin Yoo
Korean J Intern Med. 2015;30(1):104-109. Published online December 30, 2014
Background/Aims: To evaluate the impact on mortality of anti-tumor necrosis factor (anti-TNF) treatment of rheumatoid arthritis-associated interstitial lung disease (RA-ILD).
Methods: We retrospectively reviewed the medical records of 100 RA-ILD patients who visited our tertiary care medical center..
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Early effects of tumor necrosis factor inhibition on bone homeostasis after soluble tumor necrosis factor receptor use
Mie Jin Lim, Seong Ryul Kwon, Kowoon Joo, Min Jung Son, Shin-Goo Park, Won Park
Korean J Intern Med. 2014;29(6):807-813. Published online October 31, 2014
Background/Aims: Our aim was to assess whether short-term treatment with soluble tumor necrosis factor (TNF) receptor affects circulating markers of bone metabolism in rheumatoid arthritis (RA) patients.
Methods: Thirty-three active RA patients, treated with oral disease-modifying antirheumatic dru..
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Efficacy and safety of tofacitinib for active rheumatoid arthritis with an inadequate response to methotrexate or disease-modifying antirheumatic drugs: a meta-analysis of randomized controlled trials
Gwan Gyu Song, Sang-Cheol Bae, Young Ho Lee
Korean J Intern Med. 2014;29(5):656-663. Published online August 28, 2014
Background/Aims: The aim of this study was to assess the efficacy and safety of tofacitinib (5 and 10 mg twice daily) in patients with active rheumatoid arthritis (RA).
Methods: A systematic review of randomized controlled trials (RCTs) that examined the efficacy and safety of tofacitinib in patien..
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SKI306X inhibition of glycosaminoglycan degradation in human cartilage involves down-regulation of cytokine-induced catabolic genes
Choong Hyeok Choi, Tae-Hwan Kim, Yoon-Kyoung Sung, Chan-Bum Choi, Young-In Na, Hunseung Yoo, Jae-Bum Jun
Korean J Intern Med. 2014;29(5):647-655. Published online August 28, 2014
Background/Aims: SKI306X, a mixed extract of three herbs, Clematis mandshurica (CM), Prunella vulgaris (PV), and Trichosanthes kirilowii (TK), is chondroprotective in animal models of osteoarthritis (OA). The objectives of this study were to invest..
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Resting energy expenditure is not associated with disease activity in women with rheumatoid arthritis: cross-sectional study
Jung-Yoon Choe, Sung-Hoon Park, Hwajeong Lee, Hyun Hee Kwon, Seong-Kyu Kim
Korean J Intern Med. 2014;29(4):516-524. Published online June 27, 2014
Background/Aims: Increased resting energy expenditure (REE) in rheumatoid arthritis (RA) patients is thought to be caused by hypermetabolism associated with production of proinflammatory cytokines. Our aim in the present study was to explore the possible association between REE and disease activity ..
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Unusual metatarsophalangeal joint deformity in an advanced rheumatoid foot
Seung-Min Jung, Jae Hoon Ahn, Sung-Hwan Park, Kyung-Su Park
Korean J Intern Med. 2014;29(3):402-403. Published online April 29, 2014
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Etc. - Orthopedic
Evaluation of the effect of D-002, a mixture of beeswax alcohols, on osteoarthritis symptoms
Roberto Puente, José Illnait, Rosa Mas, Daisy Carbajal, Sarahí Mendoza, Julio César Fernández, Meilis Mesa, Rafael Gámez, Pablo Reyes
Korean J Intern Med. 2014;29(2):191-202. Published online February 27, 2014
Background/Aims: Nonsteroidal anti-inflammatory drugs relieve osteoarthritis (OA) symptoms but cause adverse effects. D-002, a mixture of beeswax alcohols, is effective against experimental OA. A pilot study found that D-002 (50 mg/day) for 8 weeks improves OA symptoms. The aim of this study was to ..
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